ING5 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Cell lysate)
ING5 MaxPab polyclonal antibody. Western Blot analysis of ING5 expression in Jurkat.
Western Blot (Transfected lysate)
Western Blot analysis of ING5 expression in transfected 293T cell line (H00084289-T01) by ING5 MaxPab polyclonal antibody.
Lane 1: ING5 transfected lysate(26.4 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ING5 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ING5 protein.
Immunogen
ING5 (NP_115705.2, 1 a.a. ~ 240 a.a) full-length human protein.
Sequence
MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDFESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ING5 MaxPab polyclonal antibody. Western Blot analysis of ING5 expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of ING5 expression in transfected 293T cell line (H00084289-T01) by ING5 MaxPab polyclonal antibody.
Lane 1: ING5 transfected lysate(26.4 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ING5 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ING5
Entrez GeneID
84289GeneBank Accession#
NM_032329.4Protein Accession#
NP_115705.2Gene Name
ING5
Gene Alias
FLJ23842, p28ING5
Gene Description
inhibitor of growth family, member 5
Omim ID
608525Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations.
Wang X, Castro MA, Mulder KW, Markowetz F.
PLoS Computational Biology 2012 Jun; 8(6):e1002566.
Application：ChIP, Human, Human keratinocytes.
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Diverse epigenetic strategies interact to control epidermal differentiation.
Mulder KW, Wang X, Escriu C, Ito Y, Schwarz RF, Gillis J, Sirokmány G, Donati G, Uribe-Lewis S, Pavlidis P, Murrell A, Markowetz F, Watt FM.
Nature Cell Biology 2012 Jun; 14(7):753.
Application：ChIP, Human, Human keratinocytes.
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Moz and Retinoic Acid Coordinately Regulate H3K9 Acetylation, Hox Gene Expression, and Segment Identity.
Voss AK, Collin C, Dixon MP, Thomas T.
Developmental Cell 2009 Nov; 17(5):674.
Application：ChIP, Mouse, Mouse embryos.
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Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations.
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