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ANTXR1 Pre-design Chimera RNAi

  • Catalog # : H00084168-R04
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  • Specification
  • Product Description:
  • Homo sapiens anthrax toxin receptor 1 (ANTXR1), transcript variant 3, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_018153
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • ANTXR1
  • Gene Alias:
  • ATR,FLJ10601,FLJ11298,FLJ21776,TEM8
  • Gene Description:
  • anthrax toxin receptor 1
  • Gene Summary:
  • This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq
  • Other Designations:
  • 2310008J16Rik,2810405N18Rik,tumor endothelial marker 8
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