GTF2IRD2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Cell lysate)
GTF2IRD2 MaxPab polyclonal antibody. Western Blot analysis of GTF2IRD2 expression in Hela S3 NE.
Western Blot (Transfected lysate)
Western Blot analysis of GTF2IRD2 expression in transfected 293T cell line (H00084163-T01) by GTF2IRD2 MaxPab polyclonal antibody.
Lane 1: GTF2IRD2 transfected lysate(54.78 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to GTF2IRD2 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GTF2IRD2 protein.
Immunogen
GTF2IRD2 (AAH67859, 1 a.a. ~ 498 a.a) full-length human protein.
Sequence
MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNGLLEAGAGGLLEAGSLRPAWATWQDPISTKNLKISWKQWLTPVAPATWQAEAGGSLELRSLRQQRTIIAILHSSLGDRTRPCL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GTF2IRD2 MaxPab polyclonal antibody. Western Blot analysis of GTF2IRD2 expression in Hela S3 NE.Western Blot (Transfected lysate)
Western Blot analysis of GTF2IRD2 expression in transfected 293T cell line (H00084163-T01) by GTF2IRD2 MaxPab polyclonal antibody.
Lane 1: GTF2IRD2 transfected lysate(54.78 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to GTF2IRD2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — GTF2IRD2
Entrez GeneID
84163GeneBank Accession#
BC067859Protein Accession#
AAH67859Gene Name
GTF2IRD2
Gene Alias
FLJ21423, FLJ37938, FP630, GTF2IRD2A, MGC75203
Gene Description
GTF2I repeat domain containing 2
Omim ID
608899Gene Ontology
HyperlinkGene Summary
This gene is unusual in that its coding sequence is mostly derived from Charlie8 repeat elements. However, there is mRNA and EST evidence to suggest that this gene is transcribed, and the encoded protein has a homolog in mouse, with which it shares 78% sequence identity. The exact function of this gene product is not known. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. These three genes are clustered together on chr 7q11.23. [provided by RefSeq
Other Designations
GTF2IRD2 alpha|general transcription factor II i repeat domain 2 alpha|transcription factor GTF2IRD2
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Interactome
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Publication Reference
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The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation.
Carmona-Mora P, Widagdo J, Tomasetig F, Canales CP, Cha Y, Lee W, Alshawaf A, Dottori M, Whan RM, Hardeman EC, Palmer SJ.
Human Genetics 2015 Oct; 134(10):1099.
Application：WB, Human, HeLa cells.
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GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.
Palmer SJ, Taylor KM, Santucci N, Widagdo J, Chan YK, Yeo JL, Adams M, Gunning PW, Hardeman EC.
Journal of Cell Science 2016 Aug; 125(Pt21):5040.
Application：IHC-Fr, Rat, Muscle tissue.
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The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation.
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