PCGF6 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PCGF6 partial ORF ( NP_001011663, 225 a.a. - 324 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AVPQPVPSSKGRSKKVLESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLEQYQTLREIRR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PCGF6
Entrez GeneID
84108GeneBank Accession#
NM_001011663Protein Accession#
NP_001011663Gene Name
PCGF6
Gene Alias
MBLR, MGC15678, MGC17541, RNF134
Gene Description
polycomb group ring finger 6
Omim ID
607816Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
Mel18 and Bmi1-like RING finger protein|OTTHUMP00000020394|OTTHUMP00000020395|ring finger protein 134
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