FBXO30 MaxPab mouse polyclonal antibody (B01)
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More Files
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Western Blot (Tissue lysate)
FBXO30 MaxPab polyclonal antibody. Western Blot analysis of FBXO30 expression in human colon.
Western Blot (Transfected lysate)
Western Blot analysis of FBXO30 expression in transfected 293T cell line (H00084085-T01) by FBXO30 MaxPab polyclonal antibody.
Lane 1: FBXO30 transfected lysate(81.95 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human FBXO30 protein.
Immunogen
FBXO30 (NP_115521.3, 1 a.a. ~ 745 a.a) full-length human protein.
Sequence
MEEELQHSHCVNCVSRRCMTRPEPGISCDLIGCPLVCGAVFHSCKADEHRLLCPFERVPCLNSDFGCPFTMARNKVAEHLEMCPASVVCCTMEWNRWPVSYADRKSYENLSRDVDEVAQLDMALALQDQRMLLESLKVATMMSKATDKVSKPREQISVKSSVPEIPHANGLVSVDEESYGALYQATVETTRSLAAALDILNTATRDIGMLNTSVPNDMDEQQNARESLEDQNLKDQDHLYEEEIGAVGGIDYNDTNQNAQSEQNGSSDLLCDLNTSSYDTSALCNGFPLENICTQVIDQNQNLHGDSKQSNLTNGDCVASSDGTSKPSSSLAVAAQLREIIPSSALPNGTVQHILMPDDEGEGELCWKKVDLGDVKNVDVLSFSHAPSFNFLSNSCWSKPKEDKAVDTSDLEVAEDPMGLQGIDLITAALLFCLGDSPGGRGISDSRMADIYHIDVGTQTFSLPSAILATSTMVGEIASASACDHANPQLSNPSPFQTLGLDLVLECVARYQPKQRSMFTFVCGQLFRRKEFSSHFKNVHGDIHAGLNGWMEQRCPLAYYGCTYSQRRFCPSIQGAKIIHDRHLRSFGVQPCVSTVLVEPARNCVLGLHNDHLSSLPFEVLQHIAGFLDGFSLCQLSCVSKLMRDVCGSLLQSRGMVILQWGKRKYPEGNSSWQIKEKVWRFSTAFCSVNEWKFADILSMADHLKKCSYNVVEKREEAIPLPCMCVTRELTKEGRSLRSVLKPVL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
FBXO30 MaxPab polyclonal antibody. Western Blot analysis of FBXO30 expression in human colon.Western Blot (Transfected lysate)
Western Blot analysis of FBXO30 expression in transfected 293T cell line (H00084085-T01) by FBXO30 MaxPab polyclonal antibody.
Lane 1: FBXO30 transfected lysate(81.95 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — FBXO30
Entrez GeneID
84085GeneBank Accession#
NM_032145.4Protein Accession#
NP_115521.3Gene Name
FBXO30
Gene Alias
FLJ41030, Fbx30, MGC21674
Gene Description
F-box protein 30
Omim ID
609101Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. [provided by RefSeq
Other Designations
F-box domain protein|F-box only protein 30|F-box only protein, helicase, 18|OTTHUMP00000017362
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Interactome
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Publication Reference
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Suramin and NF449 Are IP5K Inhibitors That Disrupt IP6-mediated Regulation of Cullin RING Ligase and Sensitize Cancer Cells to MLN4924/pevonedistat.
Xiaozhe Zhang, Shaodong Shi, Yang Su, Xiaoli Yang, Sining He, Jing Wu, Jian Zhang, Feng Rao.
The Journal of Biological Chemistry 2020 Jul; 295(30):10281.
Application：WB, Human, HCT116 cells.
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Suramin and NF449 Are IP5K Inhibitors That Disrupt IP6-mediated Regulation of Cullin RING Ligase and Sensitize Cancer Cells to MLN4924/pevonedistat.
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