DTNBP1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DTNBP1 full-length
Host
Human
Theoretical MW (kDa)
38.72
Interspecies Antigen Sequence
Mouse (79); Rat (79)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DTNBP1 antibody (H00084062-B01) by Western Blots.
SDS-PAGE Gel
DTNBP1 transfected lysate.
Western Blot
Lane 1: DTNBP1 transfected lysate ( 38.72 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — DTNBP1
Entrez GeneID
84062GeneBank Accession#
NM_032122.3Protein Accession#
NP_115498.2Gene Name
DTNBP1
Gene Alias
DBND, DKFZp564K192, FLJ30031, HPS7, MGC20210, My031, SDY
Gene Description
dystrobrevin binding protein 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016062|dysbindin
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Interactome
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Disease
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