KREMEN1 monoclonal antibody (M01), clone 1E7
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KREMEN1 is approximately 0.03ng/ml as a capture antibody.
Western Blot detection against Immunogen (34.76 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KREMEN1.
Immunogen
KREMEN1 (NP_114434, 310 a.a. ~ 391 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
INQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGSNSWAPPMGAGSHRVE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (85)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.76 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KREMEN1 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — KREMEN1
Entrez GeneID
83999GeneBank Accession#
NM_032045Protein Accession#
NP_114434Gene Name
KREMEN1
Gene Alias
FLJ31863, KREMEM1, KREMEN, KRM1
Gene Description
kringle containing transmembrane protein 1
Omim ID
609898Gene Ontology
HyperlinkGene Summary
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000028977|kringle-coding gene marking the eye and the nose|kringle-containing transmembrane protein 1
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Interactome
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Disease
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