FCAMR DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human FCAMR DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — FCAMR
Entrez GeneID
83953GeneBank Accession#
NM_032029.3Protein Accession#
NP_114418.2Gene Name
FCAMR
Gene Alias
FCA/MR, FKSG87
Gene Description
Fc receptor, IgA, IgM, high affinity
Omim ID
605484Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin receptor gene family involved in the microbial immune response. The protein localizes to the cell surface, where it functions as a receptor for IgM and IgA antibodies. The mouse homolog of this protein can bind and internalize IgM-coated particles, and mediates endocytosis of IgM-coated Staphylococcus by primary B lymphocytes. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Other Designations
Fc alpha/mu receptor|immunity related factor|receptor for Fc fragment of IgA and IgM
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Disease
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