FCAMR (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human FCAMR partial ORF ( NP_114418.1, 63 a.a. - 170 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TLRPSSPLCWREESSFAAPNSLKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNQYTHHRYRDRVALTDFPQRGLFVVRLSQLSPDDIGC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.62
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FCAMR
Entrez GeneID
83953GeneBank Accession#
NM_032029Protein Accession#
NP_114418.1Gene Name
FCAMR
Gene Alias
FCA/MR, FKSG87
Gene Description
Fc receptor, IgA, IgM, high affinity
Omim ID
605484Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin receptor gene family involved in the microbial immune response. The protein localizes to the cell surface, where it functions as a receptor for IgM and IgA antibodies. The mouse homolog of this protein can bind and internalize IgM-coated particles, and mediates endocytosis of IgM-coated Staphylococcus by primary B lymphocytes. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Other Designations
Fc alpha/mu receptor|immunity related factor|receptor for Fc fragment of IgA and IgM
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Disease
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