FCAMR rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human FCAMR peptide using ARM Technology.
Immunogen
A synthetic peptide of human FCAMR is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human FCAMR peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — FCAMR
Entrez GeneID
83953GeneBank Accession#
FCAMRGene Name
FCAMR
Gene Alias
FCA/MR, FKSG87
Gene Description
Fc receptor, IgA, IgM, high affinity
Omim ID
605484Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin receptor gene family involved in the microbial immune response. The protein localizes to the cell surface, where it functions as a receptor for IgM and IgA antibodies. The mouse homolog of this protein can bind and internalize IgM-coated particles, and mediates endocytosis of IgM-coated Staphylococcus by primary B lymphocytes. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Other Designations
Fc alpha/mu receptor|immunity related factor|receptor for Fc fragment of IgA and IgM
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Disease
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