HDAC10 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HDAC10 peptide using ARM Technology.
Immunogen
A synthetic peptide of human HDAC10 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HDAC10 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HDAC10
Entrez GeneID
83933GeneBank Accession#
HDAC10Gene Name
HDAC10
Gene Alias
DKFZp761B039, MGC149722
Gene Description
histone deacetylase 10
Omim ID
608544Gene Ontology
HyperlinkGene Summary
Acetylation of histone core particles modulates chromatin structure and gene expression. The opposing enzymatic activities of histone acetyltransferases and histone deacetylases, such as HDAC10, determine the acetylation status of histone tails (Kao et al., 2002 [PubMed 11677242]).[supplied by OMIM
Other Designations
OTTHUMP00000028555
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Interactome
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Disease
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