SETDB2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SETDB2 partial ORF (NP_114121.1, 620 a.a. - 719 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SETDB2
Entrez GeneID
83852GeneBank Accession#
NM_031915Protein Accession#
NP_114121.1Gene Name
SETDB2
Gene Alias
C13orf4, CLLD8, CLLL8, DKFZp586I0123, DKFZp761J1217, KMT1F
Gene Description
SET domain, bifurcated 2
Omim ID
607865Gene Ontology
HyperlinkGene Summary
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM
Other Designations
CLLL8 protein|OTTHUMP00000018417
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Interactome
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