SETDB2 monoclonal antibody (M22A), clone 1H3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SETDB2.
Immunogen
SETDB2 (NP_114121.1, 620 a.a. ~ 719 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — SETDB2
Entrez GeneID
83852GeneBank Accession#
NM_031915Protein Accession#
NP_114121.1Gene Name
SETDB2
Gene Alias
C13orf4, CLLD8, CLLL8, DKFZp586I0123, DKFZp761J1217, KMT1F
Gene Description
SET domain, bifurcated 2
Omim ID
607865Gene Ontology
HyperlinkGene Summary
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM
Other Designations
CLLL8 protein|OTTHUMP00000018417
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Interactome
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Disease
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