JAM3 monoclonal antibody (M01), clone 1D3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant JAM3.
Immunogen
JAM3 (NP_116190, 82 a.a. ~ 180 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELT*
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged JAM3 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — JAM3
Entrez GeneID
83700GeneBank Accession#
NM_032801Protein Accession#
NP_116190Gene Name
JAM3
Gene Alias
FLJ14529, JAM-C, JAMC
Gene Description
junctional adhesion molecule 3
Omim ID
606871Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. [provided by RefSeq
Other Designations
junctional adhesion molecule C
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Interactome
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Pathway
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Disease
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