RASSF5 monoclonal antibody (M01), clone 5C2
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More Files
- More Functions
Western Blot detection against Immunogen (37.51 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RASSF5.
Immunogen
RASSF5 (NP_113625, 100 a.a. ~ 206 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (84)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.51 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — RASSF5
Entrez GeneID
83593GeneBank Accession#
NM_031437Protein Accession#
NP_113625Gene Name
RASSF5
Gene Alias
MGC10823, MGC17344, Maxp1, NORE1, NORE1A, NORE1B, RAPL, RASSF3
Gene Description
Ras association (RalGDS/AF-6) domain family member 5
Omim ID
607020Gene Ontology
HyperlinkGene Summary
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034534|OTTHUMP00000034535|Rap1-binding protein|Ras association (RalGDS/AF-6) domain family 5|Ras effector-like protein|novel Ras effector 1|regulator for cell adhesion and polarization enriched in lymphoid tissue|tumor suppressor RASSF3
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Interactome
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Pathway
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Disease
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