RASSF5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human RASSF5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human RASSF5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human RASSF5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — RASSF5
Entrez GeneID
83593GeneBank Accession#
RASSF5Gene Name
RASSF5
Gene Alias
MGC10823, MGC17344, Maxp1, NORE1, NORE1A, NORE1B, RAPL, RASSF3
Gene Description
Ras association (RalGDS/AF-6) domain family member 5
Omim ID
607020Gene Ontology
HyperlinkGene Summary
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034534|OTTHUMP00000034535|Rap1-binding protein|Ras association (RalGDS/AF-6) domain family 5|Ras effector-like protein|novel Ras effector 1|regulator for cell adhesion and polarization enriched in lymphoid tissue|tumor suppressor RASSF3
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