C1orf25 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human C1orf25 protein.
Immunogen
C1orf25 (AAH45535.1, 1 a.a. ~ 733 a.a) full-length human protein.
Sequence
MENMAEEELLPLEKEEVEVAQVQVPTPARDSAGVPAPAPDSALDSAPTPASAPAPAPALAQAPALSPSLASAPEEAKSKRHISIQRQLADLENLAFVTDGNFDSASSLNSDNLDAGNRQACPLCPKEKFRACNSHKLRRHLQNLHWKVSVEFEGYRMCICHLPCRPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKGETKSSYIAASTAKPPKEILKEADTDVQVCPNYSIPQKTDSYFNPKMKLNRQLIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQENCHLNKLKVVVDSKEKEKSDDILEEGEKNLGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLFESLHHGLDDIQTLIKTLIFESECTPQSQFSIHASSNVNKQEENGVFIKTTDDTTTDNYIAQGKRKSNEMITNLGKKQKTDVSTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLKYSTPTYTGGQSESHVQSASEDTVTERVEMSVNDKAEASGCRRW
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
C1orf25 MaxPab polyclonal antibody. Western Blot analysis of C1orf25 expression in Hela S3 NE.Western Blot (Transfected lysate)
Western Blot analysis of C1orf25 expression in transfected 293T cell line (H00081627-T01) by C1orf25 MaxPab polyclonal antibody.
Lane 1: C1orf25 transfected lysate(80.63 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to C1orf25 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]Immunofluorescence
Immunofluorescence of purified MaxPab antibody to C1orf25 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — C1orf25
Entrez GeneID
81627GeneBank Accession#
BC045535.1Protein Accession#
AAH45535.1Gene Name
C1orf25
Gene Alias
MGC25112, MGC57134, MST070, MSTP070, TRM1L, bG120K12.3
Gene Description
chromosome 1 open reading frame 25
Omim ID
611673Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions. Alternatively spliced transcripts have been identified for this gene, but their full-length nature is not known. [provided by RefSeq
Other Designations
N2,N2-dimethylguanosine tRNA methyltransferase-like|OTTHUMP00000033400|TRM1-like
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Interactome
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Publication Reference
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TRMT1-catalyzed tRNA modifications are required for redox homeostasis to ensure proper cellular proliferation and oxidative stress survival.
Dewe JM, Fuller BL, Lentini JM, Kellner SM, Fu D.
Molecular and Cellular Biology 2017 Nov; 37(21):e00214.
Application:IF, Human, HeLa cells.
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TRMT1-catalyzed tRNA modifications are required for redox homeostasis to ensure proper cellular proliferation and oxidative stress survival.
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