PLA2G12A (Human) Recombinant Protein (P01)
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Specification
Product Description
Human PLA2G12A full-length ORF ( NP_110448.2, 1 a.a. - 189 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MALLSRPALTLLLLLMAAVVRCQEQAQTTDWRATLKTIRNGVHKIDTYLNAALDLLGGEDGLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKSKNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPYLDSQRAACRCHYEEKTDL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
47.5
Interspecies Antigen Sequence
Mouse (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PLA2G12A
Entrez GeneID
81579GeneBank Accession#
NM_030821.3Protein Accession#
NP_110448.2Gene Name
PLA2G12A
Gene Alias
GXII, PLA2G12, ROSSY
Gene Description
phospholipase A2, group XIIA
Omim ID
611652Gene Ontology
HyperlinkGene Summary
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM
Other Designations
group XII secreted phospholipase A2|group XIIA secreted phospholipase A2
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Interactome
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Pathway
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Disease
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