HM13 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human HM13 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARGKNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTIRSEGISLQHLKQLSREPVQGLG
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — HM13
Entrez GeneID
81502GeneBank Accession#
NM_178582.1Protein Accession#
NP_848697.1Gene Name
HM13
Gene Alias
H13, IMP1, IMPAS, MSTP086, PSENL3, PSL3, SPP, dJ324O17.1
Gene Description
histocompatibility (minor) 13
Omim ID
607106Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000030527|OTTHUMP00000030528|intramembrane protease|minor histocompatibility antigen 13|presenilin-like protein 3|signal peptide peptidase beta
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