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HM13 rabbit monoclonal antibody

  • Catalog # : H00081502-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human HM13 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human HM13 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human HM13 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • GeneBank Accession#:
  • HM13
  • Gene Name:
  • HM13
  • Gene Alias:
  • H13,IMP1,IMPAS,MSTP086,PSENL3,PSL3,SPP,dJ324O17.1
  • Gene Description:
  • histocompatibility (minor) 13
  • Gene Summary:
  • The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000030527,OTTHUMP00000030528,intramembrane protease,minor histocompatibility antigen 13,presenilin-like protein 3,signal peptide peptidase beta
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