ILKAP monoclonal antibody (M02), clone 3B5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ILKAP.
Immunogen
ILKAP (NP_110395, 293 a.a. ~ 392 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVVRIGH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to ILKAP on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ILKAP is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — ILKAP
Entrez GeneID
80895GeneBank Accession#
NM_030768Protein Accession#
NP_110395Gene Name
ILKAP
Gene Alias
DKFZp434J2031, FLJ10181, MGC4846, PP2C-DELTA
Gene Description
integrin-linked kinase-associated serine/threonine phosphatase 2C
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq
Other Designations
integrin-linked kinase-associated protein phosphatase 2C|protein phosphatase 2c, delta isozyme
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