DUSP16 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human DUSP16 partial ORF ( NP_085143.1, 561 a.a. - 665 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.29
Interspecies Antigen Sequence
Mouse (91); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DUSP16
Entrez GeneID
80824GeneBank Accession#
NM_030640Protein Accession#
NP_085143.1Gene Name
DUSP16
Gene Alias
KIAA1700, MGC129701, MGC129702, MKP-7, MKP7
Gene Description
dual specificity phosphatase 16
Omim ID
607175Gene Ontology
HyperlinkGene Summary
The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.[supplied by OMIM
Other Designations
MAPK phosphatase-7
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Interactome
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Pathway
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Disease
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