STARD5 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-STARD5 full-length
Host
Human
Theoretical MW (kDa)
23.54
Interspecies Antigen Sequence
Mouse (83); Rat (84)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-STARD5 antibody (H00080765-B01) by Western Blots.
SDS-PAGE Gel
STARD5 transfected lysate.
Western Blot
Lane 1: STARD5 transfected lysate ( 23.54 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — STARD5
Entrez GeneID
80765GeneBank Accession#
NM_181900.2Protein Accession#
NP_871629.1Gene Name
STARD5
Gene Alias
MGC10327
Gene Description
StAR-related lipid transfer (START) domain containing 5
Omim ID
607050Gene Ontology
HyperlinkGene Summary
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM
Other Designations
START domain containing 5|StAR-related lipid transfer protein 5
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