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STARD5 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00080765-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-STARD5 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 23.54
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-STARD5 antibody (H00080765-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00080765-T01
    STARD5 transfected lysate.
    Western Blot
    QC Testing of H00080765-T01
    Lane 1: STARD5 transfected lysate ( 23.54 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • STARD5
  • Gene Alias:
  • MGC10327
  • Gene Description:
  • StAR-related lipid transfer (START) domain containing 5
  • Gene Summary:
  • Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM
  • Other Designations:
  • START domain containing 5,StAR-related lipid transfer protein 5
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