TSEN2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TSEN2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TSEN2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TSEN2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TSEN2
Entrez GeneID
80746GeneBank Accession#
TSEN2Gene Name
TSEN2
Gene Alias
MGC2776, MGC4440, PCH2B, SEN2, SEN2L
Gene Description
tRNA splicing endonuclease 2 homolog (S. cerevisiae)
Omim ID
608753Gene Ontology
HyperlinkGene Summary
This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene
Other Designations
tRNA splicing endonuclease 2 homolog
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Interactome
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