COASY (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human COASY partial ORF ( NP_079509, 461 a.a. - 564 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AEGKRVCVIDAAVLLEAGWQNLVHEVWTAVIPETEAVRRIVERDGLSEAAAQSRLQSQMSGQQLVEQSHVVLSTLWEPHITQRQVEKAWALLQKRIPKTHQALD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.18
Interspecies Antigen Sequence
Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — COASY
Entrez GeneID
80347GeneBank Accession#
NM_025233Protein Accession#
NP_079509Gene Name
COASY
Gene Alias
DPCK, FLJ35179, NBP, PPAT, UKR1, pOV-2
Gene Description
Coenzyme A synthase
Omim ID
609855Gene Ontology
HyperlinkGene Summary
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM
Other Designations
bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase|coenzyme A synthase|nucleotide binding protein|phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase
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Interactome
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Pathway
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Disease
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