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COASY rabbit monoclonal antibody

  • Catalog # : H00080347-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human COASY peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human COASY is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human COASY peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • COASY
  • Gene Name:
  • COASY
  • Gene Alias:
  • DPCK,FLJ35179,NBP,PPAT,UKR1,pOV-2
  • Gene Description:
  • Coenzyme A synthase
  • Gene Summary:
  • Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM
  • Other Designations:
  • bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase,coenzyme A synthase,nucleotide binding protein,phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase
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