COASY purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human COASY protein.
Immunogen
COASY (NP_001035996.1, 1 a.a. ~ 269 a.a) full-length human protein.
Sequence
MAINRFRLENDLEELALYQIQLLKDLRHTENEEDKVSSSSFRQRMLGNLLRPPYERPELPTCLYVIGLTGISGSGKSSIAQRLKGLGAFVIDSDHLGHRAYAPGGPAYQPVVEAFGTDILHKDGIINRKVLGSRVFGNKKQLKILTDIMWPIIAKLAREEMDRAVAEGKRVCVIDAAVLLEAGWQNLVHEVWTAVIPETEAVRRIVERDGLSEAAAQSRLQSQMSGQQLVEQSHVVLSTLWEPHITQRQVEKAWALLQKRIPKTHQALD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (85)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
COASY MaxPab polyclonal antibody. Western Blot analysis of COASY expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of COASY expression in transfected 293T cell line (H00080347-T01) by COASY MaxPab polyclonal antibody.
Lane 1: COASY transfected lysate(29.59 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — COASY
Entrez GeneID
80347GeneBank Accession#
NM_001042531.1Protein Accession#
NP_001035996.1Gene Name
COASY
Gene Alias
DPCK, FLJ35179, NBP, PPAT, UKR1, pOV-2
Gene Description
Coenzyme A synthase
Omim ID
609855Gene Ontology
HyperlinkGene Summary
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM
Other Designations
bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase|coenzyme A synthase|nucleotide binding protein|phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase
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Disease
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