PNPLA3 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human PNPLA3 full-length ORF ( AAH65195.1, 1 a.a. - 481 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MYDAERGWSLSFAGCGFLGFYHVGATRCLSEHAPHLLRDARMLFGASAGALHCVGVLSGIPLEQTLQVLSDLVRKARSRNIGIFHPSFNLSKFLRQGLGKCLPANVHQLISGKIGISLTRVSDGENVLVSDFRSKDEVVDALVCSCFMPFYSGLIPPSFRGVRYVDGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKSTNFLHVDITKLSLRLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAFRFLEEKGICNRPQPGLKSSSEGMDPEVAMPSWANMSLDSSPESAALAVRLEGDELLDHLRLSILPWDESILDTLSPRLATALSEEMKDKGGYMSKICNLLPIRIMSYVMLPCTLPVESAIAIVQRLVTWLPDMPDDVLWLQWVTSQVFTRVLMCLLPASRSQMPVSSQQASPCTPEQDWPCWTPCSPEGCPAETKAEATPRSILRSSLNFFLGNKVPAGAEGLSTFPSFSLEKSL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
79.2
Interspecies Antigen Sequence
Mouse (67); Rat (65)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PNPLA3
Entrez GeneID
80339GeneBank Accession#
BC065195.1Protein Accession#
AAH65195.1Gene Name
PNPLA3
Gene Alias
ADPN, C22orf20, iPLA(2)epsilon
Gene Description
patatin-like phospholipase domain containing 3
Omim ID
609567Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq
Other Designations
OTTHUMP00000028602|adiponutrin
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Interactome
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Pathway
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Disease
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Publication Reference
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Adiponutrin: A multimeric plasma protein.
Winberg ME, Khalaj Motlagh M, Stenkula KG, Holm C, Jones HA.
Biochemical and Biophysical Research Communications 2014 Apr; 446(4):1114.
Application:IS, Human, Plasma.
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Adiponutrin: A multimeric plasma protein.
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