KCNIP4 MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human KCNIP4 protein.
Immunogen
KCNIP4 (NP_079497.2, 1 a.a. ~ 250 a.a) full-length human protein.
Sequence
MNVRRVESISAQLEEASSTGGFLYAQNSTKRSIKERLMKLLPCSAAKTSSPAIQNSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KCNIP4 expression in transfected 293T cell line (H00080333-T01) by KCNIP4 MaxPab polyclonal antibody.
Lane 1: KCNIP4 transfected lysate(27.5 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to KCNIP4 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — KCNIP4
Entrez GeneID
80333GeneBank Accession#
NM_025221.5Protein Accession#
NP_079497.2Gene Name
KCNIP4
Gene Alias
CALP, KCHIP4, MGC44947
Gene Description
Kv channel interacting protein 4
Omim ID
608182Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000158705|a-type potassium channel modulatory protein 4|calsenilin-like protein|potassium channel interacting protein 4|potassium channel-interacting protein 4
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Interactome
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Disease
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