PDGFD MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human PDGFD protein.
Immunogen
PDGFD (NP_149126.1, 1 a.a. ~ 364 a.a) full-length human protein.
Sequence
MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDDLYRRDETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASETNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMYLDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSSRPPR
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PDGFD expression in transfected 293T cell line (H00080310-T02) by PDGFD MaxPab polyclonal antibody.
Lane 1: PDGFD transfected lysate(42.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PDGFD transfected lysate using anti-PDGFD MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PDGFD purified MaxPab mouse polyclonal antibody (B01P) (H00080310-B01P). -
Gene Info — PDGFD
Entrez GeneID
80310GeneBank Accession#
NM_033135.3Protein Accession#
NP_149126.1Gene Name
PDGFD
Gene Alias
IEGF, MGC26867, MSTP036, SCDGF-B, SCDGFB
Gene Description
platelet derived growth factor D
Omim ID
609673Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq
Other Designations
iris-expressed growth factor|spinal cord derived growth factor B|spinal cord-derived growth factor-B
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Platelet-derived Growth Factor Primes Cancer-associated Fibroblasts for Apoptosis.
Rizvi S, Mertens JC, Bronk SF, Hirsova P, Dai H, Roberts LR, Kaufmann SH, Gores GJ.
The Journal of Biological Chemistry 2014 Aug; 289(33):22835.
Application:IF, Human, Cholangiocarcinoma, Liver.
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Platelet-derived Growth Factor Primes Cancer-associated Fibroblasts for Apoptosis.
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