C1orf22 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human C1orf22 full-length ORF ( AAH16464.1, 1 a.a. - 122 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGGFKYGDEQPRSDWRSYRRNLEHAVLELTLFKTVPSKMEIHSSPFKCSTAPPCNTSGQGKITEHSCEPDFCCLWIDKKQNSFSSGVGNRSLDSLLIKGSSPFLVLGVRGSFGKMHPSIVAF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
39.9
Interspecies Antigen Sequence
Mouse (46); Rat (46)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — EDEM3
Entrez GeneID
80267GeneBank Accession#
BC016464.1Protein Accession#
AAH16464.1Gene Name
EDEM3
Gene Alias
C1orf22
Gene Description
ER degradation enhancer, mannosidase alpha-like 3
Omim ID
610214Gene Ontology
HyperlinkGene Summary
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM
Other Designations
ER degradation-enhancing -mannosidase-like protein 3
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