ZC3H12A (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ZC3H12A full-length ORF (BAB15581.1, 1 a.a. - 599 a.a.) recombinant protein with GST tag at N-terminal.
Sequence
MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSPSSQSSSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDWLPQTLDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGRSPWGRADSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
92.2
Interspecies Antigen Sequence
Mouse (82); Rat (82)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ZC3H12A
Entrez GeneID
80149GeneBank Accession#
AK026884.1Protein Accession#
BAB15581.1Gene Name
ZC3H12A
Gene Alias
FLJ23231, MCPIP, MCPIP1, RP3-423B22.1, dJ423B22.1
Gene Description
zinc finger CCCH-type containing 12A
Omim ID
610562Gene Ontology
HyperlinkGene Summary
ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM
Other Designations
MCP induced protein 1|MCP-1 treatment-induced protein|MCP-induced protein 1|OTTHUMP00000004398|OTTHUMP00000004399
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Interactome
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Publication Reference
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Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1.
Happel C, Ramalingam D, Ziegelbauer JM.
PLoS Biology 2016 Nov; 14(11):e2000998.
Application：Func, Labeled pre-miRNAs.
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Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1.
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