PGAP1 monoclonal antibody (M01), clone 5G6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PGAP1.
Immunogen
PGAP1 (NP_079265, 168 a.a. ~ 266 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VAIIGHSMGGLVARALLTLKNFKHDLINLLITQATPHVAPVMPLDRFITDFYTTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPKLSHHTSAL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PGAP1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — PGAP1
Entrez GeneID
80055GeneBank Accession#
NM_024989Protein Accession#
NP_079265Gene Name
PGAP1
Gene Alias
Bst1, FLJ42774, ISPD3024
Gene Description
post-GPI attachment to proteins 1
Omim ID
611655Gene Ontology
HyperlinkGene Summary
PGAP1 catalyzes the inositol deacylation of glycosylphosphatidylinositol (GPI) at an early step in GPI biosynthesis. Inositol deacylation is essential for the generation of mature GPI capable of attachment to proteins (Tanaka et al., 2004 [PubMed 14734546]).[supplied by OMIM
Other Designations
GPI deacylase|GPI inositol-deacylase
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Interactome
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Pathway
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Disease
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