L2HGDH DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human L2HGDH DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MVPALRYLVGACGRARGRFAGGSPGACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLYEYCQQKGISYKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRGLMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPIVIKNTKGEEIRCQYVVTCAGLYSDRISELSGCTPDPRIVPFRGDYLLLKPEKCYLVKGNIYPVPDSRFPFLGVHFTPRMDGSIWLGPNAVLAFKREGYRPFDFSATDVMDIIINSGLIKLASQNFSYGVTEMYKACFLGATVKYLQKFIPEITISDILRQVAVRGPSWLWQQPMKVSDNNIYCFLWRCFALLLTGSTCSFK
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — L2HGDH
Entrez GeneID
79944GeneBank Accession#
BC006117.1Protein Accession#
AAH06117.1Gene Name
L2HGDH
Gene Alias
C14orf160, DURANIN, FLJ12618
Gene Description
L-2-hydroxyglutarate dehydrogenase
Gene Ontology
HyperlinkGene Summary
This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation. [provided by RefSeq
Other Designations
2-hydroxyglutarate dehydrogenase|L-alpha-hydroxyglutarate dehydrogenase|alpha-hydroxyglutarate oxidoreductase|alpha-ketoglutarate reductase
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Interactome
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Pathway
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