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PDZD3 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00079849-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PDZD3 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 54.12
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PDZD3 antibody (H00079849-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00079849-T01
    PDZD3 transfected lysate.
    Western Blot
    QC Testing of H00079849-T01
    Lane 1: PDZD3 transfected lysate ( 52.5 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • PDZD3
  • Gene Alias:
  • FLJ22756,IKEPP,PDZK2
  • Gene Description:
  • PDZ domain containing 3
  • Gene Summary:
  • Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM
  • Other Designations:
  • PDZ domain containing 2,intestinal and kidney enriched PDZ protein,natrium-phosphate cotransporter IIa C-terminal-associated protein 2
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