PDZD3 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of PDZD3 expression in transfected 293T cell line (H00079849-T02) by PDZD3 MaxPab polyclonal antibody.
Lane 1: PDZD3 transfected lysate(52.50 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PDZD3 protein.
Immunogen
PDZD3 (NP_079067.2, 1 a.a. ~ 491 a.a) full-length human protein.
Sequence
MEKAADLQDTASLTLKFKFNPKLGIDNPVLSLAEDHDPYDPWSLERPRFCLLSKEEGKSFGFHLQQELGRAGHVVCRVDPGTSAQRQGLQEGDRILAVNNDVVEHEDYAVVVRRIRASSPRVLLTVLARHAHDVARAQLGEDAHLCPTLGPGVRPRLCHIVKDEGGFGFSVTHGNQGPFWLVLSTGGAAERAGVPPGARLLEVNGLWQSGQQVTLLVAGPEVEEQCRQLGLPLAAPLAEGWALPTKPRCLHLEKGPQGFGFLLREEKGLDGRPGQFLWEVDPGLPAKKAGMQAGDRLVAVAGESVEGLGHEETVSRIQGQGSCVSLTVVDPEADRFFSMVRLSPLLFLENTEAPASPQGSSSASLVETEDPSLEDTSVPSVPLGSRQCFLYPGPGGSYGFRLSCVASGPRLFISQVTPGGSAARAGLQVGDVILEVNGYPVGGQNDLERLQQLPEAEPPLCLKLAARSLRGLEAWIPPGAAEDWALASDLL
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PDZD3 expression in transfected 293T cell line (H00079849-T02) by PDZD3 MaxPab polyclonal antibody.
Lane 1: PDZD3 transfected lysate(52.50 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PDZD3
Entrez GeneID
79849GeneBank Accession#
NM_024791Protein Accession#
NP_079067.2Gene Name
PDZD3
Gene Alias
FLJ22756, IKEPP, PDZK2
Gene Description
PDZ domain containing 3
Omim ID
607146Gene Ontology
HyperlinkGene Summary
Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM
Other Designations
PDZ domain containing 2|intestinal and kidney enriched PDZ protein|natrium-phosphate cotransporter IIa C-terminal-associated protein 2
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