PDZD3 (Human) Matched Antibody Pair
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Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human PDZD3.
Reactivity
Human
Quality Control Testing
Standard curve using recombinant protein ( H00079849-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-PDZD3 (100 ug)
2. Detection antibody: mouse purified polyclonal anti-PDZD3 (20 ug)
*Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — PDZD3
Entrez GeneID
79849Gene Name
PDZD3
Gene Alias
FLJ22756, IKEPP, PDZK2
Gene Description
PDZ domain containing 3
Omim ID
607146Gene Ontology
HyperlinkGene Summary
Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM
Other Designations
PDZ domain containing 2|intestinal and kidney enriched PDZ protein|natrium-phosphate cotransporter IIa C-terminal-associated protein 2
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