NHEJ1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NHEJ1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NHEJ1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NHEJ1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NHEJ1
Entrez GeneID
79840GeneBank Accession#
NHEJ1Gene Name
NHEJ1
Gene Alias
FLJ12610, XLF
Gene Description
nonhomologous end-joining factor 1
Omim ID
611290Gene Ontology
HyperlinkGene Summary
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq
Other Designations
Cernunnos|XRCC4-like factor
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Interactome
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Pathway
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Disease
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