NHEJ1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human NHEJ1 protein.
Immunogen
NHEJ1 (NP_079058.1, 1 a.a. ~ 299 a.a) full-length human protein.
Sequence
MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKELNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWNFHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (73); Rat (75)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NHEJ1 expression in transfected 293T cell line (H00079840-T01) by NHEJ1 MaxPab polyclonal antibody.
Lane 1: XLF transfected lysate(32.89 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to NHEJ1 on HepG2 cell. [antibody concentration 10 ug/ml] -
Gene Info — NHEJ1
Entrez GeneID
79840GeneBank Accession#
NM_024782.1Protein Accession#
NP_079058.1Gene Name
NHEJ1
Gene Alias
FLJ12610, XLF
Gene Description
nonhomologous end-joining factor 1
Omim ID
611290Gene Ontology
HyperlinkGene Summary
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq
Other Designations
Cernunnos|XRCC4-like factor
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