PEAK1 monoclonal antibody (M03), clone 3G6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PEAK1.
Immunogen
PEAK1 (NP_079052.2, 1151 a.a. ~ 1250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAGSSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (91)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KIAA2002 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — PEAK1
Entrez GeneID
79834GeneBank Accession#
NM_024776.3Protein Accession#
NP_079052.2Gene Name
PEAK1
Gene Alias
FLJ21140, FLJ34483, KIAA2002
Gene Description
NKF3 kinase family member
Gene Ontology
HyperlinkOther Designations
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Interactome
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Disease
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Publication Reference
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PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d.
Huang L, Wen C, Yang X, Lou Q, Wang X, Che J, Chen J, Yang Z, Wu X, Huang M, Lan P, Wang L, Iwamoto A, Wang J, Liu H.
Cell Death & Disease 2018 Feb; 9(3):271.
Application:WB-Ce, WB-Tr, Human, Caco-2, HCT-116 cells.
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Quantitative Phosphoproteomics Reveals a Cluster of Tyrosine Kinases That Mediates Src Invasive Activity in Advanced Colon Carcinoma Cells.
Leroy C, Fialin C, Sirvent A, Simon V, Urbach S, Poncet J, Robert B, Jouin P, Roche S.
Cancer Research 2009 Mar; 69(6):2279.
Application:IP, WB-Tr, Human, SW620 cells.
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PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d.
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