EHMT1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
EHMT1 transfected lysate.
Western Blot
Lane 1: EHMT1 transfected lysate ( 88.99 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-EHMT1 full-length
Host
Human
Theoretical MW (kDa)
88.99
Interspecies Antigen Sequence
Mouse (84); Rat (81)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-EHMT1 antibody (H00079813-B01) by Western Blots.
SDS-PAGE Gel
EHMT1 transfected lysate.
Western Blot
Lane 1: EHMT1 transfected lysate ( 88.99 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — EHMT1
Entrez GeneID
79813GeneBank Accession#
BC047504.1Protein Accession#
AAH47504.1Gene Name
EHMT1
Gene Alias
DEL9q34, DKFZp667M072, EUHMTASE1, Eu-HMTase1, FLJ12879, FP13812, GLP, KIAA1876, KMT1D, bA188C12.1
Gene Description
euchromatic histone-lysine N-methyltransferase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
G9a like protein|OTTHUMP00000022711|euchromatic histone methyltransferase 1
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Interactome
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Pathway
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Disease
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