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NEIL1 rabbit monoclonal antibody

  • Catalog # : H00079661-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NEIL1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NEIL1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NEIL1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • GeneBank Accession#:
  • NEIL1
  • Gene Name:
  • NEIL1
  • Gene Alias:
  • FLJ22402,FPG1,NEI1,hFPG1
  • Gene Description:
  • nei endonuclease VIII-like 1 (E. coli)
  • Gene Summary:
  • NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM
  • Other Designations:
  • endonuclease VIII,nei endonuclease VIII-like 1
  • Gene Pathway
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