IRX3 monoclonal antibody (M08), clone 2H3
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant IRX3.
Immunogen
IRX3 (NP_077312, 182 a.a. ~ 285 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDCKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.18 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
IRX3 monoclonal antibody (M08), clone 2H3 Western Blot analysis of IRX3 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged IRX3 is approximately 0.03ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to IRX3 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — IRX3
Entrez GeneID
79191GeneBank Accession#
NM_024336Protein Accession#
NP_077312Gene Name
IRX3
Gene Alias
IRX-1
Gene Description
iroquois homeobox 3
Gene Ontology
HyperlinkGene Summary
IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM
Other Designations
iroquois homeobox protein 3
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Disease
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