BRCC3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human BRCC3 full-length ORF ( NP_077308.1, 1 a.a. - 316 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAEKVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSESLHGPRDFWSSSQHISIEGQKEEERYERIEIPIHIVPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMQELSSLE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
62.5
Interspecies Antigen Sequence
Mouse (89); Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — BRCC3
Entrez GeneID
79184GeneBank Accession#
NM_024332.2Protein Accession#
NP_077308.1Gene Name
BRCC3
Gene Alias
BRCC36, C6.1A, CXorf53
Gene Description
BRCA1/BRCA2-containing complex, subunit 3
Omim ID
300617Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This protein is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
BRCA1/BRCA2-containing complex subunit 36|OTTHUMP00000061450|c6.1A
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