BRCC3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human BRCC3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human BRCC3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human BRCC3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — BRCC3
Entrez GeneID
79184GeneBank Accession#
BRCC3Gene Name
BRCC3
Gene Alias
BRCC36, C6.1A, CXorf53
Gene Description
BRCA1/BRCA2-containing complex, subunit 3
Omim ID
300617Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This protein is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
BRCA1/BRCA2-containing complex subunit 36|OTTHUMP00000061450|c6.1A
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Interactome
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