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Last updated: 2016/10/23

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CARD14 Pre-design Chimera RNAi

  • Catalog # : H00079092-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens caspase recruitment domain family, member 14 (CARD14), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_024110
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • CARD14
  • Gene Alias:
  • Gene Description:
  • caspase recruitment domain family, member 14
  • Gene Summary:
  • The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • CARD-containing MAGUK 2 protein,bcl10-interacting maguk protein 2,card-maguk protein 2,caspase recruitment domain protein 14
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