WDR77 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human WDR77 peptide using ARM Technology.
Immunogen
A synthetic peptide of human WDR77 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human WDR77 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — WDR77
Entrez GeneID
79084GeneBank Accession#
WDR77Gene Name
WDR77
Gene Alias
HKMT1069, MEP50, MGC2722, Nbla10071, RP11-552M11.3, p44
Gene Description
WD repeat domain 77
Gene Ontology
HyperlinkGene Summary
WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).[supplied by OMIM
Other Designations
OTTHUMP00000013472|androgen receptor cofactor p44|methylosome protein 50
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