MLPH purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
MLPH MaxPab polyclonal antibody. Western Blot analysis of MLPH expression in human spleen.
Western Blot (Transfected lysate)
Western Blot analysis of MLPH expression in transfected 293T cell line (H00079083-T01) by MLPH MaxPab polyclonal antibody.
Lane 1: MLPH transfected lysate(66 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MLPH protein.
Immunogen
MLPH (NP_077006.1, 1 a.a. ~ 600 a.a) full-length human protein.
Sequence
MGKKLDLSKLTDEEAQHVLEVVQRDFDLRRKEEERLEALKGKIKKESSKRELLSDTAHLNETHCARCLQPYQLLVNSKRQCLECGLFTCKSCGRVHPEEQGWICDPCHLARVVKIGSLEWYYEHVKARFKRFGSAKVIRSLHGRLQGGAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEARDSPQSLTDESCSEKAAPHKAEGLEEADTGASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAALGSNVIRNEQLPLQYLADVDTSDEESIRAHVMASHHSKRRGRASSESQIFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEEALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRIAALRAAGLTVKPSGKPRRKSNLPIFLPRVAGKLGKRPEDPNADPSSEAKAMAVPYLLRRKFSNSLKSQGKDDDSFDRKSVYRGSLTQRNPNARKGMASHTFAKPVVAHQS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (63); Rat (64)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
MLPH MaxPab polyclonal antibody. Western Blot analysis of MLPH expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of MLPH expression in transfected 293T cell line (H00079083-T01) by MLPH MaxPab polyclonal antibody.
Lane 1: MLPH transfected lysate(66 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MLPH
Entrez GeneID
79083GeneBank Accession#
NM_024101Protein Accession#
NP_077006.1Gene Name
MLPH
Gene Alias
MGC2771, MGC59733, SLAC2-A
Gene Description
melanophilin
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
exophilin-3
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Interactome
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Disease
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