SECISBP2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SECISBP2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SECISBP2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SECISBP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SECISBP2
Entrez GeneID
79048GeneBank Accession#
SECISBP2Gene Name
SECISBP2
Gene Alias
DKFZp686C09169, SBP2
Gene Description
SECIS binding protein 2
Gene Ontology
HyperlinkGene Summary
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. [provided by RefSeq
Other Designations
OTTHUMP00000021618|OTTHUMP00000064929|OTTHUMP00000064930|OTTHUMP00000064931|OTTHUMP00000064932|selenocysteine insertion sequence binding protein 2
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Interactome
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Disease
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