Products

Immunoprecipitation-Western Blot

Entrez GeneID

Gene Name

DDX54

Gene Alias

DP97, MGC2835

Gene Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 54

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq

Other Designations

ATP-dependent RNA helicase|DEAD box helicase 97 KDa